3 edition of Basic research on lung surfactant found in the catalog.
Basic research on lung surfactant
International Symposium on Basic Research on Lung Surfactant (3rd 1988 Marburg, Germany)
Includes bibliographical references and index.
|Statement||3rd International Symposium on Basic Research on Lung Surfactant, Marburg, September 12-14, 1988 ; volume editors, P. von Wichert, B. Müller.|
|Series||Progress in respiration research ;, vol. 25|
|Contributions||Wichert, P. von, Müller, B. 1952-|
|LC Classifications||QP121.A1 P7 vol. 25, QP752.P84 P7 vol. 25|
|The Physical Object|
|Pagination||xi, 360 p. :|
|Number of Pages||360|
|LC Control Number||89024565|
The pulmonary extracellular matrix (ECM) determines the tissue architecture of the lung, and provides mechanical stability and elastic recoil, which are essential for physiological lung function. Biochemical and biomechanical signals initiated by the ECM direct cellular function and differentiation, and thus play a decisive role in lung development, tissue remodelling processes and maintenance. Pulmonary surfactants and their role in pathophysiology of lung disorders Aparna Akella & Shripad B Deshpande* Department of Physiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi , India Surfactant is an agent that decreases the surface tension between two media. The surface tension between gaseous-.
Surfactant is a unique lipid and protein substance made by type II cells in the lung that provides inflation stability, decreases the work of breathing, and has components with innate host defense properties. Explore the latest full-text research PDFs, articles, conference papers, preprints and more on LUNG DEVELOPMENT. Find methods information, sources, references or conduct a literature review on.
Pulmonary surfactant is a surface-active lipoprotein complex (phospholipoprotein) formed by type II alveolar proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions. By adsorbing to the air-water interface of alveoli, with hydrophilic head groups in the water and the hydrophobic tails facing towards the air, the main lipid component of surfactant. Basic research in behavioral medicine (Leonard Epstein, PhD) Birth asphyxia and neonatal resuscitation Lung surfactant therapy administered to premature babies to assist breathing in the first critical hours after birth. UB Online Phone Book; UB Academic Health Center.
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Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease.
Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effectively!5/5(1). 3rd International Symposium on Basic Research on Lung Surfactant, Marburg, September; volume editors, P.
von Wichert, B. Müller. Reviews User-contributed reviews. Book Description. Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease.
Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this title presents coverage on surfactant-related lung disease.
It reviews basic concepts of surface tension, surfactants, and surfactant film behavior; and presents experimental methods and materials used in lung surfactant research. Basic Research on Lung Surfuctant. von Wichert and B. Miiller (Editors).
Bawl: Karger,pp. (Prog. Respir. Res., vol. 2% Lung surfactant is the material that lowers tension at the alveolar air-water interface and thereby stabilizes the lung. This volume contains papers delivered by the great. Animal-derived lung surfactants annually s infants with neonatal respiratory distress syndrome (NRDS) in the US.
Lung surfactants have further potential in treating aboutadult. Calf lung surfactant extract was found to be inhibited by plasma proteins and by a lowering of temperature.
Severe breathing difficulties and malfunctioning surfactant developed in BALB/c mice inhaling ozone or infected with respiratory syncytial virus, mainly as a result of proteins invading the airways.
Patients with asthma were challenged. LUNG SURFACTANT: BASIC RESEARCH IN THE PATHOGENESIS OF LUNG DISORDERS, VOLUME L Edited by B MULLER and P, VON WICHERT, Farm ington, Connecticut: S, Karger Publishers,pp, ,00 This book deals with the implications of basic research on pulmonary surfactant in the pathogenesis of lung disorders, which was discussed.
Discovery of lung surfactant deficiency as a main cause of neonatal respiratory distress syndrome (NRDS) has influenced a steep increase in lung surfactant research.
Although this has yielded impactful scientific discoveries, much of the basic research on lung surfactants has failed to translate into clinical practices. Pathological examination forms a key element in the final diagnosis of a variety of malignant and non-malignant respiratory disorders, and directs treatment.
Research has contributed to important advances in the pathological diagnosis of these respiratory disorders. This book is a complete overview of diagnostic procedures and pathological examination data, which help support the clinician in.
In addition to investigating the activity and delivery of clinical exogenous surfactants, research is also attempting to develop new synthetic or semi-synthetic surfactants for treating lung injury ([46, 47, –] for review).
Synthetic lung surfactants manufactured under controlled conditions in the laboratory have significant potential. Lung surfactant: basic research in the pathogenesis of lung disorders B. MUELLER AND P. VON WICHERT, eds Basel: Kargel,pages, $, This book rounds up some of the main issues discussed at an international meeting on lung sur- factant, held in Marburg, Germany It is.
Lung Surfactants: Basic Science and Clinical Applications (Lung Biology in Health and Disease): Medicine & Health Science Books @ iews: 1. Soon scientists showed that a lack of surfactant is involved in human lung disease. "At that point the research, to use the trite term, exploded," Clements says.
StoryCorps. Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants discovered some 50 years ago, this practical reference presents cutting-edge coverage of surfactant-related lung disease as well as a review of basic concepts of surfactants and surfactant film behavior in lung : $ Ladanyi, E., Suzuki, Möbius, D., Schäfer, K., Stalder, K., Presence, localization and possible role of Sp-A and Sp-B in the human lung surfactant surface layer.
An electronmicroscopic study using immuno-gold double labelling, 60 Years of Surfactant Research, Floating congress on the river Rhine, 11–17 November Google Scholar. II. Surfactant dysfunction in ALI/ARDS. There are a number of pathways by which lung surfactant activity can be compromised during acute pulmonary injury, as summarized schematically in Figures 1 and and2.
ments in lung surfactant activity, and reductions in the content or composition of active large surfactant aggregates, have been reported in BAL, edema fluid, or.
Pulmonary surfactant is a complex of highly active phospholipids and proteins that cover the alveolar epithelial surface of the lungs 1. Surfactant is synthesized in the alveolar type-II cells, stored in the lamellar bodies, and secreted to the alveolar space where it undergoes complex changes 2.
The composition of lung surfactant in humans is very constant, although it may change in disease. Lung surfactant, a lipo-protein complex, is a highly surface-active material found in the fluid lining the air-liquid interface of the alveolar surface.
Surfactant plays a dual function of preventing alveolar collapse during breathing cycle and protection of the lungs from injuries and infections caused by foreign bodies and pathogens. Varying degrees of structure-function abnormalities of. The second edition of The Lung: Development, Aging and the Environment provides an understanding of the multi-faceted nature of lung development, aging, and how the environment influences these processes.
As an essential resource to respiratory, pulmonary, and thoracic scientists and physicians it provides an interface between the “normal” and “disease” cluster of chapters, allowing.
Since the first edition of this book was published inthere has been a spectacular development in both basic research on the pulmonary surfactant system and the clinical use of surfactant for treatment of lung diseases hence the addition of the subtitle indicating the expansion of knowledge in the field and the expanded information.Previous experience in basic research allowed him to define the minor surfactant phospholipids for the first time in the mids.
He expanded these studies to ontogeny, surface activity, turnover and recycling of surfactant phospholipids, and determined the relationship of the new surfactant indices to risk of respiratory distress syndrome. Lung surfactant coats tiny air sacs in the lung. Without it, every breath is a struggle, like blowing up millions of little balloons.
With surfactant, breathing is as easy as blowing soap bubbles.